Detection of prions in skin punch biopsies of Creutzfeldt–Jakob disease patients

Prion real‐time quaking‐induced conversion (RT‐QuIC) is an ultrasensitive assay detecting pathological aggregates of misfolded prion protein in biospecimens. We studied 71 punch biopsy skin samples of 35 patients with Creutzfeldt–Jakob disease (CJD), including five assessed in vitam. The results con...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Ann Clin Transl Neurol
Päätekijät: Mammana, Angela, Baiardi, Simone, Rossi, Marcello, Franceschini, Alessia, Donadio, Vincenzo, Capellari, Sabina, Caughey, Byron, Parchi, Piero
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2020
Aiheet:
Brief Communications
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187701/
https://ncbi.nlm.nih.gov/pubmed/32141717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51000
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