Detection of prions in skin punch biopsies of Creutzfeldt–Jakob disease patients

Prion real‐time quaking‐induced conversion (RT‐QuIC) is an ultrasensitive assay detecting pathological aggregates of misfolded prion protein in biospecimens. We studied 71 punch biopsy skin samples of 35 patients with Creutzfeldt–Jakob disease (CJD), including five assessed in vitam. The results con...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Mammana, Angela, Baiardi, Simone, Rossi, Marcello, Franceschini, Alessia, Donadio, Vincenzo, Capellari, Sabina, Caughey, Byron, Parchi, Piero
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187701/
https://ncbi.nlm.nih.gov/pubmed/32141717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51000
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