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High diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prions

An early and accurate in vivo diagnosis of rapidly progressive dementia remains challenging, despite its critical importance for the outcome of treatable forms, and the formulation of prognosis. Real-Time Quaking-Induced Conversion (RT-QuIC) is an in vitro assay that, for the first time, specificall...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Franceschini, Alessia, Baiardi, Simone, Hughson, Andrew G., McKenzie, Neil, Moda, Fabio, Rossi, Marcello, Capellari, Sabina, Green, Alison, Giaccone, Giorgio, Caughey, Byron, Parchi, Piero
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587608/
https://ncbi.nlm.nih.gov/pubmed/28878311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10922-w
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