Factors That Improve RT-QuIC Detection of Prion Seeding Activity

Rapid and sensitive detection of prions is important in managing prion diseases. The real-time quaking-induced conversion (RT-QuIC) assay for prion seeding activity has been applied to many prion diseases and provides for specific antemortem diagnostic testing. We evaluated RT-QuIC’s long-term consi...

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Bibliografiske detaljer
Udgivet i:Viruses
Main Authors: Orrú, Christina D., Hughson, Andrew G., Groveman, Bradley R., Campbell, Katrina J., Anson, Kelsie J., Manca, Matteo, Kraus, Allison, Caughey, Byron
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885095/
https://ncbi.nlm.nih.gov/pubmed/27223300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8050140
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