New generation QuIC assays for prion seeding activity

The ability of abnormal TSE-associated forms of PrP to seed the formation of amyloid fibrils from recombinant PrP(Sen) has served as the basis for several relatively rapid and highly sensitive tests for prion diseases. These tests include rPrP-PMCA (rPMCA), standard quaking-induced conversion (S-QuI...

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Detalles Bibliográficos
Publicado en:Prion
Autores principales: Orru, Christina D., Wilham, Jason M., Vascellari, Sarah, Hughson, Andrew G., Caughey, Byron
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2012
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082091/
https://ncbi.nlm.nih.gov/pubmed/22421206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.19430
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