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New generation QuIC assays for prion seeding activity
The ability of abnormal TSE-associated forms of PrP to seed the formation of amyloid fibrils from recombinant PrP(Sen) has served as the basis for several relatively rapid and highly sensitive tests for prion diseases. These tests include rPrP-PMCA (rPMCA), standard quaking-induced conversion (S-QuI...
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| Publié dans: | Prion |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7082091/ https://ncbi.nlm.nih.gov/pubmed/22421206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.19430 |
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