New generation QuIC assays for prion seeding activity

The ability of abnormal TSE-associated forms of PrP to seed the formation of amyloid fibrils from recombinant PrP(Sen) has served as the basis for several relatively rapid and highly sensitive tests for prion diseases. These tests include rPrP-PMCA (rPMCA), standard quaking-induced conversion (S-QuI...

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Библиографические подробности
Опубликовано в: :Prion
Главные авторы: Orru, Christina D., Wilham, Jason M., Vascellari, Sarah, Hughson, Andrew G., Caughey, Byron
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2012
Предметы:
Review
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082091/
https://ncbi.nlm.nih.gov/pubmed/22421206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.19430
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