New generation QuIC assays for prion seeding activity

The ability of abnormal TSE-associated forms of PrP to seed the formation of amyloid fibrils from recombinant PrP(Sen) has served as the basis for several relatively rapid and highly sensitive tests for prion diseases. These tests include rPrP-PMCA (rPMCA), standard quaking-induced conversion (S-QuI...

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Bibliografske podrobnosti
izdano v:Prion
Main Authors: Orru, Christina D., Wilham, Jason M., Vascellari, Sarah, Hughson, Andrew G., Caughey, Byron
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2012
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082091/
https://ncbi.nlm.nih.gov/pubmed/22421206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.19430
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