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RT-QuIC and Related Assays for Detecting and Quantifying Prion-like Pathological Seeds of α-Synuclein

Various disease-associated forms or strains of α-synuclein (αSyn<sup>D</sup>) can spread and accumulate in a prion-like fashion during synucleinopathies such as Parkinson’s disease (PD), Lewy body dementia (DLB), and multiple system atrophy (MSA). This capacity for self-propagation has e...

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Main Authors: Ankit Srivastava, Parvez Alam, Byron Caughey
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-04-01
Colecção:Biomolecules
Assuntos:
Acesso em linha:https://www.mdpi.com/2218-273X/12/4/576
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