High diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prions

An early and accurate in vivo diagnosis of rapidly progressive dementia remains challenging, despite its critical importance for the outcome of treatable forms, and the formulation of prognosis. Real-Time Quaking-Induced Conversion (RT-QuIC) is an in vitro assay that, for the first time, specificall...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Franceschini, Alessia, Baiardi, Simone, Hughson, Andrew G., McKenzie, Neil, Moda, Fabio, Rossi, Marcello, Capellari, Sabina, Green, Alison, Giaccone, Giorgio, Caughey, Byron, Parchi, Piero
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587608/
https://ncbi.nlm.nih.gov/pubmed/28878311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10922-w
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