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Transmission of CJD from nasal brushings but not spinal fluid or RT‐QuIC product

OBJECTIVE: The detection of prion seeding activity in CSF and olfactory mucosal brushings using real‐time quaking‐induced conversion assays allows highly accurate clinical diagnosis of sporadic Creutzfeldt–Jakob disease. To gauge transmission risks associated with these biospecimens and their testin...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Raymond, Gregory J., Race, Brent, Orrú, Christina D., Raymond, Lynne D., Bongianni, Matilde, Fiorini, Michele, Groveman, Bradley R., Ferrari, Sergio, Sacchetto, Luca, Hughson, Andrew G., Monaco, Salvatore, Pocchiari, Maurizio, Zanusso, Gianluigi, Caughey, Byron
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318090/
https://ncbi.nlm.nih.gov/pubmed/32538552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51057
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