A Test for Creutzfeldt–Jakob Disease Using Nasal Brushings

BACKGROUND: Definite diagnosis of sporadic Creutzfeldt–Jakob disease in living patients remains a challenge. A test that detects the specific marker for Creutzfeldt–Jakob disease, the prion protein (PrP(CJD)), by means of real-time quaking-induced conversion (RT-QuIC) testing of cerebrospinal fluid...

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Bibliographic Details
Main Authors: Orrú, Christina D., Bongianni, Matilde, Tonoli, Giovanni, Ferrari, Sergio, Hughson, Andrew G., Groveman, Bradley R., Fiorini, Michele, Pocchiari, Maurizio, Monaco, Salvatore, Caughey, Byron, Zanusso, Gianluigi
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186748/
https://ncbi.nlm.nih.gov/pubmed/25099576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1315200
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