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Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids

For the transmissible, neurogenerative family of prion diseases, few human models of infection exist and none represent structured neuronal tissue. Human cerebral organoids are self-organizing, three-dimensional brain tissues that can be grown from induced pluripotent stem cells. Organoids can model...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Groveman, Bradley R., Foliaki, Simote T., Orru, Christina D., Zanusso, Gianluigi, Carroll, James A., Race, Brent, Haigh, Cathryn L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6567389/
https://ncbi.nlm.nih.gov/pubmed/31196223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0742-2
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