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Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt–Jakob disease

Creutzfeldt–Jakob Disease (CJD) is a fatal, currently incurable, neurodegenerative disease. The search for candidate treatments would be greatly facilitated by the availability of human cell-based models of prion disease. Recently, an induced pluripotent stem cell derived human cerebral organoid mod...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Groveman, Bradley R., Ferreira, Natalia C., Foliaki, Simote T., Walters, Ryan O., Winkler, Clayton W., Race, Brent, Hughson, Andrew G., Zanusso, Gianluigi, Haigh, Cathryn L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7943797/
https://ncbi.nlm.nih.gov/pubmed/33727594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84689-6
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