Pharmacodynamics of ClpP-Activating Antibiotic Combinations against Gram-Positive Pathogens

It is often difficult to cure endocarditis, osteomyelitis, and device-associated infections caused by Gram-positive pathogens, despite therapy with clinically appropriate antibiotics. This may be due to antibiotic tolerance or resistance development. Acyldepsipeptides (ADEPs) are a class of bacteric...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Mroue, Nader, Arya, Anu, Brown Gandt, Autumn, Russell, Cameron, Han, Angel, Gavrish, Ekaterina, LaFleur, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2019
Ämnen:
Experimental Therapeutics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187625/
https://ncbi.nlm.nih.gov/pubmed/31611348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01554-19
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