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Pharmacodynamics of ClpP-Activating Antibiotic Combinations against Gram-Positive Pathogens

It is often difficult to cure endocarditis, osteomyelitis, and device-associated infections caused by Gram-positive pathogens, despite therapy with clinically appropriate antibiotics. This may be due to antibiotic tolerance or resistance development. Acyldepsipeptides (ADEPs) are a class of bacteric...

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Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Mroue, Nader, Arya, Anu, Brown Gandt, Autumn, Russell, Cameron, Han, Angel, Gavrish, Ekaterina, LaFleur, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187625/
https://ncbi.nlm.nih.gov/pubmed/31611348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01554-19
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