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Efficient Estimation and Applications of Cross-Validated Genetic Predictions to Polygenic Risk Scores and Linear Mixed Models

Large-scale cohorts with combined genetic and phenotypic data, coupled with methodological advances, have produced increasingly accurate genetic predictors of complex human phenotypes called polygenic risk scores (PRSs). In addition to the potential translational impacts of identifying at-risk indiv...

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Bibliografische gegevens
Gepubliceerd in:J Comput Biol
Hoofdauteurs: Mefford, Joel, Park, Danny, Zheng, Zhili, Ko, Arthur, Ala-Korpela, Mika, Laakso, Markku, Pajukanta, Päivi, Yang, Jian, Witte, John, Zaitlen, Noah
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc., publishers 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185352/
https://ncbi.nlm.nih.gov/pubmed/32077750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2019.0325
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