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Polygenic Modeling with Bayesian Sparse Linear Mixed Models
Both linear mixed models (LMMs) and sparse regression models are widely used in genetics applications, including, recently, polygenic modeling in genome-wide association studies. These two approaches make very different assumptions, so are expected to perform well in different situations. However, i...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567190/ https://ncbi.nlm.nih.gov/pubmed/23408905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003264 |
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