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Granisetron alleviates Alzheimer’s disease pathology in TgSwDI mice through calmodulin-dependent protein kinase II/cAMP-response element binding protein pathway
Alzheimer’s disease is characterized by a compromised blood-brain barrier and disrupted intracellular calcium homeostasis in the brain. Therefore, rectifying the blood-brain barrier (BBB) integrity and restoring calcium homeostasis could provide an effective strategy to treat Alzheimer’s disease. Re...
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| Veröffentlicht in: | J Alzheimers Dis |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7183768/ https://ncbi.nlm.nih.gov/pubmed/31683487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190849 |
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