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Granisetron alleviates Alzheimer’s disease pathology in TgSwDI mice through calmodulin-dependent protein kinase II/cAMP-response element binding protein pathway

Alzheimer’s disease is characterized by a compromised blood-brain barrier and disrupted intracellular calcium homeostasis in the brain. Therefore, rectifying the blood-brain barrier (BBB) integrity and restoring calcium homeostasis could provide an effective strategy to treat Alzheimer’s disease. Re...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Al Rihani, Sweilem B., Lan, Renny S., Kaddoumi, Amal
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183768/
https://ncbi.nlm.nih.gov/pubmed/31683487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190849
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