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Bayesian Design for Two-Arm Randomized Phase II Clinical Trials with Endpoints from the Exponential Family Using Multiple Constraints

Frequentist design for two-arm randomized phase II clinical trials with outcomes from the exponential dispersion family was proposed previously, where the total sample sizes are minimized under multiple constraints on the standard errors of the estimated group means and their difference. This design...

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Détails bibliographiques
Publié dans:J Biopharm Stat
Auteurs principaux: Jiang, Wei, Wick, Jo A., He, Jianghua, Mahnken, Jonathan D., Mayo, Matthew S.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182359/
https://ncbi.nlm.nih.gov/pubmed/29172970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2017.1402779
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