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Bayesian Design for Two-Arm Randomized Phase II Clinical Trials with Endpoints from the Exponential Family Using Multiple Constraints

Frequentist design for two-arm randomized phase II clinical trials with outcomes from the exponential dispersion family was proposed previously, where the total sample sizes are minimized under multiple constraints on the standard errors of the estimated group means and their difference. This design...

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Detalhes bibliográficos
Publicado no:J Biopharm Stat
Main Authors: Jiang, Wei, Wick, Jo A., He, Jianghua, Mahnken, Jonathan D., Mayo, Matthew S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182359/
https://ncbi.nlm.nih.gov/pubmed/29172970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2017.1402779
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