FADS1 promotes the progression of laryngeal squamous cell carcinoma through activating AKT/mTOR signaling

Metabolic abnormality is the major feature of laryngeal squamous cell carcinoma (LSCC), however, the underlying mechanism remain largely elusive. Fatty acid desaturase 1 (FADS1), as the key rate-limiting enzyme of polyunsaturated fatty acids (PUFAs), catalyzes dihomo-gamma-linolenic acid (DGLA) to a...

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Udgivet i:Cell Death Dis
Main Authors: Zhao, Rui, Tian, Linli, Zhao, Bo, Sun, Yanan, Cao, Jing, Chen, Kexin, Li, Fengqing, Li, Minghua, Shang, Desi, Liu, Ming
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181692/
https://ncbi.nlm.nih.gov/pubmed/32332698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2457-5
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