circPARD3 drives malignant progression and chemoresistance of laryngeal squamous cell carcinoma by inhibiting autophagy through the PRKCI-Akt-mTOR pathway

BACKGROUND: Laryngeal squamous cell carcinoma (LSCC) is the second most common malignant tumor in head and neck. Autophagy and circular RNAs (circRNAs) play critical roles in cancer progression and chemoresistance. However, the function and mechanism of circRNA in autophagy regulation of LSCC remain...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Gao, Wei, Guo, Huina, Niu, Min, Zheng, Xiwang, Zhang, Yuliang, Xue, Xuting, Bo, Yunfeng, Guan, Xiaoya, Li, Zhongxun, Guo, Yujia, He, Long, Zhang, Yu, Li, Li, Cao, Jimin, Wu, Yongyan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686732/
https://ncbi.nlm.nih.gov/pubmed/33234130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01279-2
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