circPARD3 drives malignant progression and chemoresistance of laryngeal squamous cell carcinoma by inhibiting autophagy through the PRKCI-Akt-mTOR pathway

BACKGROUND: Laryngeal squamous cell carcinoma (LSCC) is the second most common malignant tumor in head and neck. Autophagy and circular RNAs (circRNAs) play critical roles in cancer progression and chemoresistance. However, the function and mechanism of circRNA in autophagy regulation of LSCC remain...

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Detaylı Bibliyografya
Yayımlandı:Mol Cancer
Asıl Yazarlar: Gao, Wei, Guo, Huina, Niu, Min, Zheng, Xiwang, Zhang, Yuliang, Xue, Xuting, Bo, Yunfeng, Guan, Xiaoya, Li, Zhongxun, Guo, Yujia, He, Long, Zhang, Yu, Li, Li, Cao, Jimin, Wu, Yongyan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2020
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686732/
https://ncbi.nlm.nih.gov/pubmed/33234130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01279-2
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