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FOXL2 directs DNA double-strand break repair pathways by differentially interacting with Ku
The balance between major DNA double-strand break (DSB) repair pathways is influenced by binding of the Ku complex, a XRCC5/6 heterodimer, to DSB ends, initiating non-homologous end joining (NHEJ) but preventing additional DSB end resection and homologous recombination (HR). However, the key molecul...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7181608/ https://ncbi.nlm.nih.gov/pubmed/32332759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15748-1 |
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