An alternative miRISC targets a cancer‐associated coding sequence mutation in FOXL2

Recent evidence suggests that animal microRNAs (miRNAs) can target coding sequences (CDSs); however, the pathophysiological importance of such targeting remains unknown. Here, we show that a somatic heterozygous missense mutation (c.402C>G; p.C134W) in FOXL2, a feature shared by virtually all adu...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Shin, Eunkyoung, Jin, Hanyong, Suh, Dae‐Shik, Luo, Yongyang, Ha, Hye‐Jeong, Kim, Tae Heon, Hahn, Yoonsoo, Hyun, Seogang, Lee, Kangseok, Bae, Jeehyeon
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737606/
https://ncbi.nlm.nih.gov/pubmed/33215742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104719
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