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Acetaminophen (Paracetamol) metabolites induce vasodilation and hypotension by activating Kv7 potassium channels directly and indirectly

Objective: Intravenous (IV) acetaminophen (paracetamol; APAP) is well-documented to cause hypotension. Since the patients receiving intravenous APAP are usually critically ill, any severe haemodynamic changes, as with those associated with APAP, can be life threatening. The mechanism underlying this...

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Bibliografiske detaljer
Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: van der Horst, Jennifer, Manville, Rian W., Hayes, Katie, Thomsen, Morten B, Abbott, Geoffrey W., Jepps, Thomas A.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7180128/
https://ncbi.nlm.nih.gov/pubmed/32188278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.313997
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