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Acetaminophen (Paracetamol) metabolites induce vasodilation and hypotension by activating Kv7 potassium channels directly and indirectly

Objective: Intravenous (IV) acetaminophen (paracetamol; APAP) is well-documented to cause hypotension. Since the patients receiving intravenous APAP are usually critically ill, any severe haemodynamic changes, as with those associated with APAP, can be life threatening. The mechanism underlying this...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Arterioscler Thromb Vasc Biol
Egile Nagusiak: van der Horst, Jennifer, Manville, Rian W., Hayes, Katie, Thomsen, Morten B, Abbott, Geoffrey W., Jepps, Thomas A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7180128/
https://ncbi.nlm.nih.gov/pubmed/32188278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.313997
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