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Isoform-Selective KCNA1 Potassium Channel Openers Built from Glycine

Loss of function of voltage-gated potassium (Kv) channels is linked to a range of lethal or debilitating channelopathies. New pharmacological approaches are warranted to isoform-selectively activate specific Kv channels. One example is KCNA1 Potassium Voltage-Gated Channel Subfamily A Member 1 (KCNA...

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Publicat a:J Pharmacol Exp Ther
Autors principals: Manville, Rían W., Abbott, Geoffrey W.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228494/
https://ncbi.nlm.nih.gov/pubmed/32217768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.264507
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