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Novel Endochin-Like Quinolones Exhibit Potent In Vitro Activity against Plasmodium knowlesi but Do Not Synergize with Proguanil
Quinolones, such as the antimalarial atovaquone, are inhibitors of the malarial mitochondrial cytochrome bc(1) complex, a target critical to the survival of both liver- and blood-stage parasites, making these drugs useful as both prophylaxis and treatment. Recently, several derivatives of endochin h...
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| Yayımlandı: | Antimicrob Agents Chemother |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7179610/ https://ncbi.nlm.nih.gov/pubmed/32094134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02549-19 |
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