Abacavir Exposure in Children Cotreated for Tuberculosis with Rifampin and Superboosted Lopinavir-Ritonavir

In children requiring lopinavir coformulated with ritonavir in a 4:1 ratio (lopinavir-ritonavir-4:1) and rifampin, adding ritonavir to achieve a 4:4 ratio with lopinavir (LPV/r-4:4) overcomes the drug-drug interaction. Possible drug-drug interactions within this regimen may affect abacavir concentra...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Rabie, Helena, Tikiso, Tjokosela, Lee, Janice, Fairlie, Lee, Strehlau, Renate, Bobat, Raziya, Liberty, Afaaf, McIlleron, Helen, Andrieux-Meyer, Isabelle, Cotton, Mark, Lallemant, Marc, Denti, Paolo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2020
Pynciau:
Pharmacology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179606/
https://ncbi.nlm.nih.gov/pubmed/32071055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01923-19
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg