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Pharmacokinetics and Drug-Drug Interactions of Lopinavir-Ritonavir Administered with First- and Second-Line Antituberculosis Drugs in HIV-Infected Children Treated for Multidrug-Resistant Tuberculosis

Lopinavir-ritonavir forms the backbone of current first-line antiretroviral regimens in young HIV-infected children. As multidrug-resistant (MDR) tuberculosis (TB) frequently occurs in young children in high-burden TB settings, it is important to identify potential interactions between MDR-TB treatm...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: van der Laan, Louvina E., Garcia-Prats, Anthony J., Schaaf, H. Simon, Tikiso, Tjokosela, Wiesner, Lubbe, de Kock, Mine, Winckler, Jana, Norman, Jennifer, McIlleron, Helen, Denti, Paolo, Hesseling, Anneke C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786799/
https://ncbi.nlm.nih.gov/pubmed/29133558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00420-17
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