miR‐30b protects nigrostriatal dopaminergic neurons from MPP(+)‐induced neurotoxicity via SNCA

OBJECTIVE: To explore the function of miR‐30b in pathogenesis of Parkinson's disease (PD) and its underlying molecular mechanism. MATERIALS AND METHODS: We used 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPP(+)) as a tool for constructing the PD cell model, using miR‐30b mimics or inhibitors...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Brain Behav
Egile Nagusiak: Shen, Yu‐fei, Zhu, Zhuo‐ying, Qian, Shu‐xia, Xu, Cong‐ying, Wang, Yan‐ping
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177592/
https://ncbi.nlm.nih.gov/pubmed/32154657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.1567
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