Hydralazine Protects Nigrostriatal Dopaminergic Neurons From MPP(+) and MPTP Induced Neurotoxicity: Roles of Nrf2-ARE Signaling Pathway

Although the pathogenic mechanisms of Parkinson's disease (PD) remain unclear, ample empirical evidence suggests that oxidative stress is involved in the pathogenesis of this disease. The nuclear factor E2-related factor 2 (Nrf2) is known to activate several antioxidant response element (ARE)-d...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Guo, Xingfang, Han, Chao, Ma, Kai, Xia, Yun, Wan, Fang, Yin, Sijia, Kou, Liang, Sun, Yadi, Wu, Jiawei, Hu, Junjie, Huang, Jinsha, Xiong, Nian, Wang, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435581/
https://ncbi.nlm.nih.gov/pubmed/30949126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2019.00271
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