Hydralazine Protects Nigrostriatal Dopaminergic Neurons From MPP(+) and MPTP Induced Neurotoxicity: Roles of Nrf2-ARE Signaling Pathway

Although the pathogenic mechanisms of Parkinson's disease (PD) remain unclear, ample empirical evidence suggests that oxidative stress is involved in the pathogenesis of this disease. The nuclear factor E2-related factor 2 (Nrf2) is known to activate several antioxidant response element (ARE)-d...

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Vydáno v:Front Neurol
Hlavní autoři: Guo, Xingfang, Han, Chao, Ma, Kai, Xia, Yun, Wan, Fang, Yin, Sijia, Kou, Liang, Sun, Yadi, Wu, Jiawei, Hu, Junjie, Huang, Jinsha, Xiong, Nian, Wang, Tao
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Neurology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435581/
https://ncbi.nlm.nih.gov/pubmed/30949126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2019.00271
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