Iron Chelators and Antioxidants Regenerate Neuritic Tree and Nigrostriatal Fibers of MPP+/MPTP-Lesioned Dopaminergic Neurons

Neuronal death in Parkinson’s disease (PD) is often preceded by axodendritic tree retraction and loss of neuronal functionality. The presence of non-functional but live neurons opens therapeutic possibilities to recover functionality before clinical symptoms develop. Considering that iron accumulati...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Aguirre, Pabla, Mena, Natalia P., Carrasco, Carlos M., Muñoz, Yorka, Pérez-Henríquez, Patricio, Morales, Rodrigo A., Cassels, Bruce K., Méndez-Gálvez, Carolina, García-Beltrán, Olimpo, González-Billault, Christian, Núñez, Marco T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684383/
https://ncbi.nlm.nih.gov/pubmed/26658949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144848
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