Hydralazine Protects Nigrostriatal Dopaminergic Neurons From MPP+ and MPTP Induced Neurotoxicity: Roles of Nrf2-ARE Signaling Pathway

Although the pathogenic mechanisms of Parkinson's disease (PD) remain unclear, ample empirical evidence suggests that oxidative stress is involved in the pathogenesis of this disease. The nuclear factor E2-related factor 2 (Nrf2) is known to activate several antioxidant response element (ARE)-d...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Xingfang Guo, Chao Han, Kai Ma, Yun Xia, Fang Wan, Sijia Yin, Liang Kou, Yadi Sun, Jiawei Wu, Junjie Hu, Jinsha Huang, Nian Xiong, Tao Wang
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2019-03-01
श्रृंखला:Frontiers in Neurology
विषय:
Parkinson's disease
hydralazine
neuroprotection
Nrf2-ARE signaling pathway
MPTP
MPP+
ऑनलाइन पहुंच:https://www.frontiersin.org/article/10.3389/fneur.2019.00271/full
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