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Neonatal exposure to lipopolysaccharide enhances vulnerability of nigrostriatal dopaminergic neurons to rotenone neurotoxicity in later life

Brain inflammation in early life has been proposed to play important roles in the development of neurodegenerative disorders in adult life. To test this hypothesis, we used a neonatal rat model of lipopolysaccharide (LPS) exposure (1,000 EU/g body weight, intracerebral injection on P5) to produce br...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Fan, Lir-Wan, Tien, Lu-Tai, Lin, Rick C. S., Simpson, Kimberly L., Rhodes, Philip G., Cai, Zhengwei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185112/
https://ncbi.nlm.nih.gov/pubmed/21798348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.07.011
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