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Neonatal exposure to lipopolysaccharide enhances accumulation of α-synuclein aggregation and dopamine transporter protein expression in the substantia nigra in responses to rotenone challenge in later life

Brain inflammation in early life may enhance adult susceptibility to develop neurodegenerative disorders triggered by environmental toxins. Our previous studies show that perinatal lipopolysaccharide (LPS) exposure enhances adult susceptibility to rotenone-induced injury to the dopaminergic system i...

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Detalhes bibliográficos
Main Authors: Tien, Lu-Tai, Kaizaki, Asuka, Pang, Yi, Cai, Zhengwei, Bhatt, Abhay J, Fan, Lir-Wan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676711/
https://ncbi.nlm.nih.gov/pubmed/23567316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2013.03.014
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