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Neuroprotective effects of intranasal IGF-1 against neonatal lipopolysaccharide-induced neurobehavioral deficits and neuronal inflammation in the substantia nigra and locus coeruleus of juvenile rats

Neonatal lipopolysaccharide (LPS) exposure-induced brain inflammation resulted in motor dysfunction and brain dopaminergic neuronal injury, and increased the risks of neurodegenerative disorders in adult rats. Our previous studies showed that intranasal administration of insulin-like growth factor-1...

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書目詳細資料
發表在:Dev Neurosci
Main Authors: Tien, Lu-Tai, Lee, Yih-Jing, Pang, Yi, Lu, Silu, Lee, Jonathan W, Tseng, Chih-Hsueh, Bhatt, Abhay J, Savich, Renate D, Fan, Lir-Wan
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799046/
https://ncbi.nlm.nih.gov/pubmed/28787734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000477898
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