Differential neuroprotective and anti-inflammatory effects of L-type voltage dependent calcium channel and ryanodine receptor antagonists in the substantia nigra and locus coeruleus

Neuroinflammation and degeneration of catecholaminergic brainstem nuclei occur early in neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. Neuroinflammation increases levels of pro-inflammatory cytokines and reactive oxygen species which can alter neuronal calcium (Ca(+2...

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Detalhes bibliográficos
Publicado no:J Neuroimmune Pharmacol
Main Authors: Hopp, Sarah C., Royer, Sarah E., D’Angelo, Heather M., Kaercher, Roxanne M., Fisher, David A., Wenk, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336597/
https://ncbi.nlm.nih.gov/pubmed/25318607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-014-9568-7
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