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Differential rescue of spatial memory deficits in aged rats by L-type voltage dependent calcium channel and ryanodine receptor antagonism

Age-associated memory impairments may result as a consequence of neuroinflammatory induction of intracellular calcium (Ca(+2)) dysregulation. Altered L-type voltage dependent calcium channel (L-VDCC) and ryanodine receptor (RyR) activity may underlie age-associated learning and memory impairments. V...

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Publicado en:Neuroscience
Main Authors: Hopp, Sarah C., D’Angelo, Heather M., Royer, Sarah E., Kaercher, Roxanne M., Adzovic, Linda, Wenk, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250380/
https://ncbi.nlm.nih.gov/pubmed/25224829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.09.007
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