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Differential neuroprotective and anti-inflammatory effects of L-type voltage dependent calcium channel and ryanodine receptor antagonists in the substantia nigra and locus coeruleus

Neuroinflammation and degeneration of catecholaminergic brainstem nuclei occur early in neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. Neuroinflammation increases levels of pro-inflammatory cytokines and reactive oxygen species which can alter neuronal calcium (Ca(+2...

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Podrobná bibliografie
Vydáno v:J Neuroimmune Pharmacol
Hlavní autoři: Hopp, Sarah C., Royer, Sarah E., D’Angelo, Heather M., Kaercher, Roxanne M., Fisher, David A., Wenk, Gary L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336597/
https://ncbi.nlm.nih.gov/pubmed/25318607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-014-9568-7
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