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Molecular mechanisms of fentanyl mediated β-arrestin biased signaling
The development of novel analgesics with improved safety profiles to combat the opioid epidemic represents a central question to G protein coupled receptor structural biology and pharmacology: What chemical features dictate G protein or β-arrestin signaling? Here we use adaptively biased molecular d...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7176292/ https://ncbi.nlm.nih.gov/pubmed/32275713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007394 |
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