The β-blocker Nebivolol Is a GRK/β-arrestin Biased Agonist

Nebivolol, a third generation β-adrenoceptor (β-AR) antagonist (β-blocker), causes vasodilation by inducing nitric oxide (NO) production. The mechanism via which nebivolol induces NO production remains unknown, resulting in the genesis of much of the controversy regarding the pharmacological action...

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Detalhes bibliográficos
Main Authors: Erickson, Catherine E., Gul, Rukhsana, Blessing, Christopher P., Nguyen, Jenny, Liu, Tammy, Pulakat, Lakshmi, Bastepe, Murat, Jackson, Edwin K., Andresen, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748024/
https://ncbi.nlm.nih.gov/pubmed/23977191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071980
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