The β-blocker Nebivolol Is a GRK/β-arrestin Biased Agonist

Nebivolol, a third generation β-adrenoceptor (β-AR) antagonist (β-blocker), causes vasodilation by inducing nitric oxide (NO) production. The mechanism via which nebivolol induces NO production remains unknown, resulting in the genesis of much of the controversy regarding the pharmacological action...

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Detaylı Bibliyografya
Asıl Yazarlar: Erickson, Catherine E., Gul, Rukhsana, Blessing, Christopher P., Nguyen, Jenny, Liu, Tammy, Pulakat, Lakshmi, Bastepe, Murat, Jackson, Edwin K., Andresen, Bradley T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748024/
https://ncbi.nlm.nih.gov/pubmed/23977191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071980
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