Characterization of methadone as a β-arrestin-biased μ-opioid receptor agonist

BACKGROUND: Methadone is a unique µ-opioid receptor agonist. Although several researchers have insisted that the pharmacological effects of methadone are mediated through the blockade of NMDA receptor, the underlying mechanism by which methadone exerts its distinct pharmacological effects compared t...

詳細記述

保存先:
書誌詳細
出版年:Mol Pain
主要な著者: Doi, Seira, Mori, Tomohisa, Uzawa, Naoki, Arima, Takamichi, Takahashi, Tomoyuki, Uchida, Masashi, Yawata, Ayaka, Narita, Michiko, Uezono, Yasuhito, Suzuki, Tsutomu, Narita, Minoru
フォーマット: Artigo
言語:Inglês
出版事項: SAGE Publications 2016
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956382/
https://ncbi.nlm.nih.gov/pubmed/27317580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916654146
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