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Characterization of methadone as a β-arrestin-biased μ-opioid receptor agonist

BACKGROUND: Methadone is a unique µ-opioid receptor agonist. Although several researchers have insisted that the pharmacological effects of methadone are mediated through the blockade of NMDA receptor, the underlying mechanism by which methadone exerts its distinct pharmacological effects compared t...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Pain
Main Authors: Doi, Seira, Mori, Tomohisa, Uzawa, Naoki, Arima, Takamichi, Takahashi, Tomoyuki, Uchida, Masashi, Yawata, Ayaka, Narita, Michiko, Uezono, Yasuhito, Suzuki, Tsutomu, Narita, Minoru
פורמט: Artigo
שפה:Inglês
יצא לאור: SAGE Publications 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956382/
https://ncbi.nlm.nih.gov/pubmed/27317580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916654146
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