Characterization of methadone as a β-arrestin-biased μ-opioid receptor agonist

BACKGROUND: Methadone is a unique µ-opioid receptor agonist. Although several researchers have insisted that the pharmacological effects of methadone are mediated through the blockade of NMDA receptor, the underlying mechanism by which methadone exerts its distinct pharmacological effects compared t...

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Bibliografische gegevens
Gepubliceerd in:Mol Pain
Hoofdauteurs: Doi, Seira, Mori, Tomohisa, Uzawa, Naoki, Arima, Takamichi, Takahashi, Tomoyuki, Uchida, Masashi, Yawata, Ayaka, Narita, Michiko, Uezono, Yasuhito, Suzuki, Tsutomu, Narita, Minoru
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SAGE Publications 2016
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956382/
https://ncbi.nlm.nih.gov/pubmed/27317580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916654146
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