Characterization of methadone as a β-arrestin-biased μ-opioid receptor agonist

BACKGROUND: Methadone is a unique µ-opioid receptor agonist. Although several researchers have insisted that the pharmacological effects of methadone are mediated through the blockade of NMDA receptor, the underlying mechanism by which methadone exerts its distinct pharmacological effects compared t...

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Detalhes bibliográficos
Publicado no:Mol Pain
Main Authors: Doi, Seira, Mori, Tomohisa, Uzawa, Naoki, Arima, Takamichi, Takahashi, Tomoyuki, Uchida, Masashi, Yawata, Ayaka, Narita, Michiko, Uezono, Yasuhito, Suzuki, Tsutomu, Narita, Minoru
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956382/
https://ncbi.nlm.nih.gov/pubmed/27317580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916654146
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