Characterization of methadone as a β-arrestin-biased μ-opioid receptor agonist

BACKGROUND: Methadone is a unique µ-opioid receptor agonist. Although several researchers have insisted that the pharmacological effects of methadone are mediated through the blockade of NMDA receptor, the underlying mechanism by which methadone exerts its distinct pharmacological effects compared t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Pain
Prif Awduron: Doi, Seira, Mori, Tomohisa, Uzawa, Naoki, Arima, Takamichi, Takahashi, Tomoyuki, Uchida, Masashi, Yawata, Ayaka, Narita, Michiko, Uezono, Yasuhito, Suzuki, Tsutomu, Narita, Minoru
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE Publications 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956382/
https://ncbi.nlm.nih.gov/pubmed/27317580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916654146
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