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Precise genomic mapping of 5-hydroxymethylcytosine via covalent tether-directed sequencing
5-hydroxymethylcytosine (5hmC) is the most prevalent intermediate on the oxidative DNA demethylation pathway and is implicated in regulation of embryogenesis, neurological processes, and cancerogenesis. Profiling of this relatively scarce genomic modification in clinical samples requires cost-effect...
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| Publicado no: | PLoS Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7176277/ https://ncbi.nlm.nih.gov/pubmed/32275660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000684 |
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