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Precise genomic mapping of 5-hydroxymethylcytosine via covalent tether-directed sequencing
5-hydroxymethylcytosine (5hmC) is the most prevalent intermediate on the oxidative DNA demethylation pathway and is implicated in regulation of embryogenesis, neurological processes, and cancerogenesis. Profiling of this relatively scarce genomic modification in clinical samples requires cost-effect...
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| Foilsithe in: | PLoS Biol |
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| Main Authors: | , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Public Library of Science
2020
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7176277/ https://ncbi.nlm.nih.gov/pubmed/32275660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000684 |
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