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Tethered Oligonucleotide-Primed sequencing, TOP-seq: a high-resolution economical approach for DNA epigenome profiling
Modification of CG dinucleotides in DNA is part of epigenetic regulation of gene function in vertebrates and is associated with complex human disease. Bisulfite sequencing permits high resolution analysis of cytosine modification in mammalian genomes, however its utility is often limited due to subs...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5291818/ https://ncbi.nlm.nih.gov/pubmed/28111014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.12.012 |
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