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Efficient engraftment of pluripotent stem cell-derived myogenic progenitors in a novel immunodeficient mouse model of limb girdle muscular dystrophy 2I

BACKGROUND: Defects in α-dystroglycan (DG) glycosylation characterize a group of muscular dystrophies known as dystroglycanopathies. One of the key effectors in the α-DG glycosylation pathway is the glycosyltransferase fukutin-related protein (FKRP). Mutations in FKRP lead to a large spectrum of mus...

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Detalhes bibliográficos
Publicado no:Skelet Muscle
Main Authors: Azzag, Karim, Ortiz-Cordero, Carolina, Oliveira, Nelio A. J., Magli, Alessandro, Selvaraj, Sridhar, Tungtur, Sudheer, Upchurch, Weston, Iaizzo, Paul A., Lu, Qi Long, Perlingeiro, Rita C. R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175515/
https://ncbi.nlm.nih.gov/pubmed/32321586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-020-00228-3
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