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Genomic Safe Harbor Expression of PAX7 for the Generation of Engraftable Myogenic Progenitors
Inducible expression of PAX7 in differentiating pluripotent stem cells (PSCs) allows massively scalable generation of human myogenic progenitors, which upon transplantation into dystrophic muscles give rise to donor-derived myofibers and satellite cells. Therefore, PSC-derived PAX7(+) myogenic proge...
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| Publicado no: | Stem Cell Reports |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7815936/ https://ncbi.nlm.nih.gov/pubmed/33275879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.11.001 |
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