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Engraftment of ES-Derived Myogenic Progenitors in a Severe Mouse Model of Muscular Dystrophy

Controlled myogenic differentiation of mouse embryonic stem cells by Pax3 combined with purification of PDGFαR(+)Flk-1(−) paraxial mesoderm results in the efficient in vitro generation of early skeletal myogenic progenitors. Upon transplantation into dystrophin-deficient mdx mice, these progenitors...

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Bibliographic Details
Main Authors: Filareto, Antonio, Darabi, Radbod, Perlingeiro, Rita C.R.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593119/
https://ncbi.nlm.nih.gov/pubmed/23483458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2157-7633.S10-001
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