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Pluripotent stem cell-derived myogenic progenitors remodel their molecular signature upon in vivo engraftment
Optimal cell-based therapies for the treatment of muscle degenerative disorders should not only regenerate fibers but provide a quiescent satellite cell pool ensuring long-term maintenance and regeneration. Conditional expression of Pax3/Pax7 in differentiating pluripotent stem cells (PSCs) allows t...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6410870/ https://ncbi.nlm.nih.gov/pubmed/30760602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808303116 |
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